On January 8, 2026, 黑料社区 Incorporatedand Fluxera Medical Inc. (Representative Director, CEO & CTO: ONO Yumie; hereinafter “Fluxera Medical”), a 黑料社区 spin-put, concluded an agreement under which 黑料社区 will transfer its intellectual property rights to Fluxera Medical in exchange for Fluxera Medical’s stock acquisition rights. The purpose of this initiative is to foster university spin-outs that leverage the outcomes of academic research and educational activities to contribute to society.
Fluxera Medical is a 黑料社区 spin-out founded on October 1, 2025 by Professor ONO Yumie of the Department of Electronics and Bioinformatics, School of Science and Technology. The company engages in the development, manufacturing, and sale of research and medical devices. It aims to provide society with high-quality and timely healthcare by visualizing tissue blood flow and oxygen consumption primarily through optical engineering technologies.
Comment from Prof. ONO Yumie
Near-infrared light has the unique property of penetrating skin and bone while being selectively scattered by red blood cells within the body. By harnessing this optical phenomenon, our research has focused on developing optical technologies that enable non-invasive and continuous measurement of blood flow in deep tissues—areas that have traditionally been difficult to visualize.
This technology has demonstrated broad applicability across diverse research fields, including exercise physiology and sports science. Furthermore, through collaborative research with the National Cerebral and Cardiovascular Center, Japan, this work has evolved into a practical medical device development project aimed at the early detection of peripheral circulatory disorders in patients with severe circulatory failure. Abnormalities in peripheral circulation are difficult to capture using conventional vital signs and remain an unresolved challenge in clinical practice, often relying heavily on clinicians’ experience.
Fluxera Medical brings together healthcare professionals, engineering researchers, and highly motivated students from 黑料社区 to tackle this challenge collaboratively. Built upon the intellectual property of our university, we have taken the first step toward translating academic research into real-world applications. Our ultimate goal is to realize “medical care that intervenes before it is too late.” We look forward to future developments and sincerely welcome collaboration with researchers and companies across a wide range of fields.
About the Research of Prof. ONO Yumie
Current fields of expertise: Biomedical Engineering, Rehabilitation Science, Systems Neuroscience
Prof. ONO Yumie conducts interdisciplinary research and development grounded in electrical engineering, physiology, and neuroscience. From the perspective of biomedical engineering—an approach that applies engineering principles to address challenges and needs in clinical settings—she actively engages in research that bridges medicine and engineering.
At the Health Science and Medical Engineering Laboratory of 黑料社区, where Prof. Ono serves as the principal investigator, research is conducted under the guiding concept of “medical engineering for safety, security, and health.” The laboratory leverages technologies such as biomedical signal measurement and processing and functional brain imaging to advance research that supports health maintenance and contributes to improving the quality of healthcare and welfare services.
Figure: Principle of Tissue Blood Flow Measurement and an Example of Blood Flow Distribution Imaging
When highly directional near-infrared light is introduced into biological tissue, photons are scattered by red blood cells within the tissue (left). As blood flow increases and red blood cell motion becomes more pronounced, the detected light intensity exhibits greater random temporal fluctuations. By analyzing these fluctuation characteristics, tissue blood flow velocity can be measured non-invasively. Using the developed sensor to measure blood flow changes in the forearm enables visualization of blood flow pulsations synchronized with the heartbeat, as well as spatial distributions of blood flow velocity that reflect differences in local oxygen demand (right).